A novel protein secretion system is responsible for the secretion of chitinase A, an important virulence factor of Salmonella Typhimurium
The research group led by Dr. Tobias Geiger, in cooperation with the research group of Prof. Dr. Christine Josenhans, published new results that show the secretion of chitinase A, a newly described virulence factor of pathogenic Salmonella Typhimurium, by a novel protein secretion system. Once secreted, this chitinase mediates the adhesion of Salmonella to human host cells as well as the bacterial invasion into the cells. The results of the study have been published in the journal PLOS Pathogens (https://doi.org/10.1371/journal.ppat.1011306).
